Effect of prostaglandin I2(PGI2) and its analog thia-prostaglandin (Thia-PGI2) on platelet aggregates
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چکیده
منابع مشابه
Prostacyclin (prostaglandin I2, PGI2) inhibits platelet adhesion and thrombus formation on subendothelium.
Prostaglandin I2 (prostacyclin, PGI2), a substance synthesized in the wall of blood vessels, has been previously shown to inhibit the aggregation of platelets in stirred platelet-rich plasma. We used a method in which segments of deendothelialized rabbit aorta are perfused at arterial shear rates with human blood and found that both platelet adhesion and thrombus formation on subendothelium was...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1979
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)67450-0